Dermatitis Herpetiformis (Duhring's Diesease) is a chronic blistering skin condition, characterised by blisters filled with a watery fluid. Despite its name, DH is neither related to nor caused by herpes virus: the name means that it is a skin inflammation having an appearance similar to herpes.
DH was first described by Dr. Louis Adolphus Duhring in 1884. A connection between DH and gluten intolerance (celiac disease) was recognised in 1967, although the exact causal mechanism is not known.
The age of onset is usually about 15-40, but DH can also affect children and the elderly. Men and women are equally affected. Estimates of DH prevalence vary from 1 in 400 to 1 in 10000. It is most common in patients of northern European ancestry, and is associated with the HLA-DQ2 haplotype along with celiac disease and gluten sensitivity.